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Role of Comorbidities in the Functional Evaluation of Patients with Non-Fibrocystic Bronquiectasia
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A5044 - Role of Comorbidities in the Functional Evaluation of Patients with Non-Fibrocystic Bronquiectasia
Author Block: L. V. dos Reis, R. E. Salles, S. P. Mateus, W. Costa, R. I. Salles, R. I. Salles, A. Santos; Pneumology, University of State of Rio de Janeiro, Rio de Janeiro, Brazil.
Introduction: The presence of comorbidities in patients with non-fibrocystic bronchiectasis (NFC) could be an additional risk factor in the mortality of these patients, changing the evolution and the need for a specific therapeutic approach.To identify the main comorbidities of patients with NFC bronchiectasis and to evaluate their influence on lung function. Method: A cross-sectional study with patients from the NFC bronchiectasis outpatient clinic of the Pedro Ernesto University Hospital - UERJ. All patients had a diagnosis of bronchiectasis from computed tomography of the chest and underwent spirometry from February to May 2017, in addition to anthropometric data collection and identification of comorbidities (C +) or not (C-). Patients with exacerbation at the time of spirometry were excluded. Chi-Square and T tests were used for statistical analysis. Results: Of the 100 patients included, 72 were women and 28 men, with a mean age of 56.5 years (± 16). The mean value of body mass index (BMI) was 24.4 kg / m² ± 5.1. The mean percentage values of post-bronchodilation FEV1 (BD), post-BD FVC, and post-BD FEV1 / FVC ratio were: 56.7%, 68.5% and 66.2, respectively. 70% of the cases were C +, and cardiovascular diseases were the most prevalent (63%), followed by COPD (36%), diabetes (23%), asthma (20%), osteoarticular diseases (17%), depression ), neoplasias (10%), hypothyroidism (6%), autoimmune diseases (4%), chronic renal failure (4%) and hepatitis C (1%). The C + patients were older (60 x 49 years, p = 0.001) and had a higher BMI (25 x 22 kg / m², p = 0.002) than the C- patients. With the exception of FEV1 / FVC, which was lower in patients with comorbidities (p = 0.02), the functional values analyzed did not show a significant difference between the groups. Conclusion: In our sample, patients with NFC bronchiectasis with associated comorbidities were older and slightly overweight, which may have influenced functional respiratory values. These findings may have an impact on the quality of life and mortality of these patients.
Author Block: L. V. dos Reis, R. E. Salles, S. P. Mateus, W. Costa, R. I. Salles, R. I. Salles, A. Santos; Pneumology, University of State of Rio de Janeiro, Rio de Janeiro, Brazil.
Introduction: The presence of comorbidities in patients with non-fibrocystic bronchiectasis (NFC) could be an additional risk factor in the mortality of these patients, changing the evolution and the need for a specific therapeutic approach.To identify the main comorbidities of patients with NFC bronchiectasis and to evaluate their influence on lung function. Method: A cross-sectional study with patients from the NFC bronchiectasis outpatient clinic of the Pedro Ernesto University Hospital - UERJ. All patients had a diagnosis of bronchiectasis from computed tomography of the chest and underwent spirometry from February to May 2017, in addition to anthropometric data collection and identification of comorbidities (C +) or not (C-). Patients with exacerbation at the time of spirometry were excluded. Chi-Square and T tests were used for statistical analysis. Results: Of the 100 patients included, 72 were women and 28 men, with a mean age of 56.5 years (± 16). The mean value of body mass index (BMI) was 24.4 kg / m² ± 5.1. The mean percentage values of post-bronchodilation FEV1 (BD), post-BD FVC, and post-BD FEV1 / FVC ratio were: 56.7%, 68.5% and 66.2, respectively. 70% of the cases were C +, and cardiovascular diseases were the most prevalent (63%), followed by COPD (36%), diabetes (23%), asthma (20%), osteoarticular diseases (17%), depression ), neoplasias (10%), hypothyroidism (6%), autoimmune diseases (4%), chronic renal failure (4%) and hepatitis C (1%). The C + patients were older (60 x 49 years, p = 0.001) and had a higher BMI (25 x 22 kg / m², p = 0.002) than the C- patients. With the exception of FEV1 / FVC, which was lower in patients with comorbidities (p = 0.02), the functional values analyzed did not show a significant difference between the groups. Conclusion: In our sample, patients with NFC bronchiectasis with associated comorbidities were older and slightly overweight, which may have influenced functional respiratory values. These findings may have an impact on the quality of life and mortality of these patients.
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