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Physical Activity Measured by an Accelerometer to Monitor Patients with Pulmonary Arterial Hypertension
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A2150 - Physical Activity Measured by an Accelerometer to Monitor Patients with Pulmonary Arterial Hypertension
Author Block: S. Sehgal1, A. Chowdhury2, F. Rabih3, A. Gadre3, M. M. Park4, M. Li4, X. Wang4, K. B. Highland5; 1Pulmonary Critical Care, Temple University, Philadelphia, PA, United States, 2Respiratory Institute, Cleveland Clinic, Cleveland, OH, United States, 3Internal Medicine, Cleveland Clinic, Cleveland, OH, United States, 4Cleveland Clinic, Cleveland, OH, United States, 5Respiratory Institute/ Department of Pulmonary, Cleveland Clinic, Cleveland, OH, United States.
Rationale: Physical activity can be accurately and economically measured using accelerometers. Activity levels in patients with pulmonary arterial hypertension have correlated with surrogate markers of disease severity and quality of life measures. It is not known whether a change in physical activity measures over time correlate with a change in markers of disease severity. Our objective is to evaluate whether physical activity measured by an accelerometer correlates with a change in six-minute walk distance and other markers of disease severity. Methods: Prospective, observational study in patients with prevalent pulmonary arterial hypertension. Patients wore a wrist worn accelerometer (FitbitchargeHR®) between two outpatient visits. Daily step count and daily activity levels were recorded and the slope over time was correlated with changes in six-minute walk distance, quality of life measures and other parameters of pulmonary hypertension severity between the two visits. Results: 30 patients with PAH were enrolled, of which 20 patients had adequate accelerometer data to be analyzed. Mean duration of follow up was 138 days with a mean patient compliance of 87%. Change in daily step count between two outpatient visits correlated with a change in six minute walk distance (r 0.43, p 0.05 ). Change in duration spent in fairly active ( r 0.52, p 0.02) and lightly active ( r 0.48, p 0.05) activity and sedentary activity levels ( r -0.54 p 0.02 ) correlated with EURO-QOL quality of life measures. Conclusions: Change in daily step count and time spent at various activity levels measured by an accelerometer correlate with change in six-minute walk distance and quality of life measures in pulmonary arterial hypertension patients and thus have a potential role in monitoring patients with pulmonary hypertension.
Author Block: S. Sehgal1, A. Chowdhury2, F. Rabih3, A. Gadre3, M. M. Park4, M. Li4, X. Wang4, K. B. Highland5; 1Pulmonary Critical Care, Temple University, Philadelphia, PA, United States, 2Respiratory Institute, Cleveland Clinic, Cleveland, OH, United States, 3Internal Medicine, Cleveland Clinic, Cleveland, OH, United States, 4Cleveland Clinic, Cleveland, OH, United States, 5Respiratory Institute/ Department of Pulmonary, Cleveland Clinic, Cleveland, OH, United States.
Rationale: Physical activity can be accurately and economically measured using accelerometers. Activity levels in patients with pulmonary arterial hypertension have correlated with surrogate markers of disease severity and quality of life measures. It is not known whether a change in physical activity measures over time correlate with a change in markers of disease severity. Our objective is to evaluate whether physical activity measured by an accelerometer correlates with a change in six-minute walk distance and other markers of disease severity. Methods: Prospective, observational study in patients with prevalent pulmonary arterial hypertension. Patients wore a wrist worn accelerometer (FitbitchargeHR®) between two outpatient visits. Daily step count and daily activity levels were recorded and the slope over time was correlated with changes in six-minute walk distance, quality of life measures and other parameters of pulmonary hypertension severity between the two visits. Results: 30 patients with PAH were enrolled, of which 20 patients had adequate accelerometer data to be analyzed. Mean duration of follow up was 138 days with a mean patient compliance of 87%. Change in daily step count between two outpatient visits correlated with a change in six minute walk distance (r 0.43, p 0.05 ). Change in duration spent in fairly active ( r 0.52, p 0.02) and lightly active ( r 0.48, p 0.05) activity and sedentary activity levels ( r -0.54 p 0.02 ) correlated with EURO-QOL quality of life measures. Conclusions: Change in daily step count and time spent at various activity levels measured by an accelerometer correlate with change in six-minute walk distance and quality of life measures in pulmonary arterial hypertension patients and thus have a potential role in monitoring patients with pulmonary hypertension.
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