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Seasonal Periodicity in Pulmonary Fibrosis Mortality in the United States
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A5359 - Seasonal Periodicity in Pulmonary Fibrosis Mortality in the United States
Author Block: Z. Yaqoob1, S. Alqaisi2, A. Fadhil2, H. Altaii2; 1College of Medicine, University of Central Florida, Orlando, FL, United States, 2Cleveland Clinic, Cleveland, OH, United States.
Authors: Zaid J. Yaqoob, Sura Al-Qaisi, Ali Fadhil, Haider Altaii
Background: Pulmonary Fibrosis (PF) is a progressive disease and is associated with high mortality. As with other respiratory diseases, seasonal periodicity is expected in PF mortality. The objective of the study is to describe the seasonal differences in PF mortality.
Methods: We conducted a population-based study using data collected by Center for Disease Control and Prevention (CDC) Wide-Ranging Online data for Epidemiologic Research (WONDER), based on death certificates for US residents from 1999 to 2015. We identified all deaths due to PF as the underlying cause of death [International Classification of Diseases, 10th revision: J84.1]. We investigated the temporal, demographic, geographic, and monthly variation in PF deaths.
Results: A total of 203,069 deaths were identified, with age-adjusted mortality rate of 3.8 per 100,000. PF mortality was higher in males vs females (5.0 vs 3.0 per 100,000) and in whites vs blacks (4.0 vs 2.1 per 100,000). Most patients died in a medical facility (50%), followed by home (28%), nursing home/long term care (13%) and hospice (4%). Between 1999 and 2015, there was a slight increase PF mortality (3.3 in 1999 to 3.8 in 2015, per 100,000). PF deaths were highest in winter months compared with summer months, a finding that is consistent across the 4 major US regions (Northeast, West, Midwest, South), figure. PF mortality also varied by geographic location: highest in the Midwest (4.2 per 100,000) and lowest in Northeast (3.2 per 100,000).
Conclusions: Deaths due to Pulmonary Fibrosis exhibit seasonal periodicity with winter predominance. Further studies are needed to investigate potential environmental triggers of mortality in PF.
Author Block: Z. Yaqoob1, S. Alqaisi2, A. Fadhil2, H. Altaii2; 1College of Medicine, University of Central Florida, Orlando, FL, United States, 2Cleveland Clinic, Cleveland, OH, United States.
Authors: Zaid J. Yaqoob, Sura Al-Qaisi, Ali Fadhil, Haider Altaii
Background: Pulmonary Fibrosis (PF) is a progressive disease and is associated with high mortality. As with other respiratory diseases, seasonal periodicity is expected in PF mortality. The objective of the study is to describe the seasonal differences in PF mortality.
Methods: We conducted a population-based study using data collected by Center for Disease Control and Prevention (CDC) Wide-Ranging Online data for Epidemiologic Research (WONDER), based on death certificates for US residents from 1999 to 2015. We identified all deaths due to PF as the underlying cause of death [International Classification of Diseases, 10th revision: J84.1]. We investigated the temporal, demographic, geographic, and monthly variation in PF deaths.
Results: A total of 203,069 deaths were identified, with age-adjusted mortality rate of 3.8 per 100,000. PF mortality was higher in males vs females (5.0 vs 3.0 per 100,000) and in whites vs blacks (4.0 vs 2.1 per 100,000). Most patients died in a medical facility (50%), followed by home (28%), nursing home/long term care (13%) and hospice (4%). Between 1999 and 2015, there was a slight increase PF mortality (3.3 in 1999 to 3.8 in 2015, per 100,000). PF deaths were highest in winter months compared with summer months, a finding that is consistent across the 4 major US regions (Northeast, West, Midwest, South), figure. PF mortality also varied by geographic location: highest in the Midwest (4.2 per 100,000) and lowest in Northeast (3.2 per 100,000).
Conclusions: Deaths due to Pulmonary Fibrosis exhibit seasonal periodicity with winter predominance. Further studies are needed to investigate potential environmental triggers of mortality in PF.
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