Home
|
Inbox
|
Search
|
View Abstract
Latent Tuberculosis Infection and Vitamin D Status in Health Care Workers
Description
.abstract img { width:300px !important; height:auto; display:block; text-align:center; margin-top:10px } .abstract { overflow-x:scroll } .abstract table { width:100%; display:block; border:hidden; border-collapse: collapse; margin-top:10px } .abstract td, th { border-top: 1px solid #ddd; padding: 4px 8px; } .abstract tbody tr:nth-child(even) td { background-color: #efefef; } .abstract a { overflow-wrap: break-word; word-wrap: break-word; }
A5371 - Latent Tuberculosis Infection and Vitamin D Status in Health Care Workers
Author Block: D. Park, T. Park, J. Moon, S. Kim, T. Kim, J. Sohn, H. Yoon; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea, Seoul, Korea, Republic of.
Background: Deficient serum vitamin D levels have been associated with incidence of MTB, and latent tuberculosis infection (LTBI). However, the impact of vitamin D status on LTBI in health care workers(HCWs) is uncertain. The aim of this study was to estimate the associations of serum 25-hydroxyvitamin D3(25[OH]D) status with LTBI prevalence and conversion in Korean HCWs. Methods: The study was designed in two phases: cross-sectional and case-control. From November 2016 to December 2016, HCWs were studied in order to screen for LTBI. LTBI and conversion cases were defined following QuaniFERON-TB GIT test. Demographic, clinical data and serum 25(OH)D levels were collected in enrolled HCWs. Logistic regression models were used in the statistical analysis. Results: The study comprised 332 HCWs with 89% reported prior BCG vaccination including doctors, nurses, nurse assistants and others. Only 0.9% of HCW had a sufficient serum 25(OH)D (≥ 30ng/ml) level. The results of the cross-sectional study showed that the prevalence of LTBI in HCWs was 18.1% (60/332) and associated factors were male gender (OR 5.57), job position (nursing assistants OR 7.19, others OR 4.70, than those in doctors), older age (≥ 40 year-old OR 4.37, than those with 20-29). We did not found significant associations between LTBI status and serum 25(OH)D. After 9 months, we found that 8(4.8%) out of 168 negative LTBI HCWs presented positive conversion using QuaniFERON-TB Gold In-Tube test. However, serum 25(OH)D levels were not associated with the positive conversion of LTBI negative HCWs. Conclusions: Our study shows serum 25(OH)D levels is not related LTBI prevalence and positive conversion in Korean HCWs.
Author Block: D. Park, T. Park, J. Moon, S. Kim, T. Kim, J. Sohn, H. Yoon; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea, Seoul, Korea, Republic of.
Background: Deficient serum vitamin D levels have been associated with incidence of MTB, and latent tuberculosis infection (LTBI). However, the impact of vitamin D status on LTBI in health care workers(HCWs) is uncertain. The aim of this study was to estimate the associations of serum 25-hydroxyvitamin D3(25[OH]D) status with LTBI prevalence and conversion in Korean HCWs. Methods: The study was designed in two phases: cross-sectional and case-control. From November 2016 to December 2016, HCWs were studied in order to screen for LTBI. LTBI and conversion cases were defined following QuaniFERON-TB GIT test. Demographic, clinical data and serum 25(OH)D levels were collected in enrolled HCWs. Logistic regression models were used in the statistical analysis. Results: The study comprised 332 HCWs with 89% reported prior BCG vaccination including doctors, nurses, nurse assistants and others. Only 0.9% of HCW had a sufficient serum 25(OH)D (≥ 30ng/ml) level. The results of the cross-sectional study showed that the prevalence of LTBI in HCWs was 18.1% (60/332) and associated factors were male gender (OR 5.57), job position (nursing assistants OR 7.19, others OR 4.70, than those in doctors), older age (≥ 40 year-old OR 4.37, than those with 20-29). We did not found significant associations between LTBI status and serum 25(OH)D. After 9 months, we found that 8(4.8%) out of 168 negative LTBI HCWs presented positive conversion using QuaniFERON-TB Gold In-Tube test. However, serum 25(OH)D levels were not associated with the positive conversion of LTBI negative HCWs. Conclusions: Our study shows serum 25(OH)D levels is not related LTBI prevalence and positive conversion in Korean HCWs.
|
Home
|
Inbox
|
Search
|