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Impact of Parkinsonism on Elderly Patients Hospitalized for Pneumonia
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A4938 - Impact of Parkinsonism on Elderly Patients Hospitalized for Pneumonia
Author Block: T. Jo1, H. Yasunaga2, W. Hasegawa1, Y. Sakamoto1, H. Takeshima1, H. Urushiyama1, Y. Hiraishi1, A. Mitani1, M. Tarui1, G. Tanaka1, T. Nagase1, Y. Yamauchi1; 1Department of Respiratory Medicine, The University of Tokyo Hospital, Tokyo, Japan, 2Department of Clinical Epidemiology and Health Economics, The University of Tokyo, Tokyo, Japan.
Background: Parkinsonism increases with aging and both Parkinsonism and aging has been associated with morbidity and mortality of pneumonia. However, the impact of Parkinsonism on hospitalized elderly patients for pneumonia remain obscure. The aim of this study was to evaluate the impact of Parkinsonism on the course of elderly patients hospitalized for pneumonia. Methods: Using the Japanese Diagnosis Procedure Combination database, we created a matched pair cohort in patients aged 60 years or older hospitalized for pneumonia with or without Parkinsonism. In-hospital mortalities, discharge status, length of stay and total cost during hospitalization were evaluated. We performed a multivariable logistic regression analysis to assess the association between 28-day in-hospital mortality and Parkinsonism. Results: In-hospital mortality for 7, 14 and 28 days were not higher in elderly patients hospitalized for pneumonia with Parkinsonism. However, Patients with Parkinsonism showed significantly longer length of stay, higher total cost during hospitalization and were less likely to discharge home. Multivariate analysis revealed a lower risk for in-hospital mortality in patients with Parkinsonism. Conclusions: We demonstrated that Parkinsonism was not necessarily a risk for in-hospital mortality in pneumonia patients. However, comorbid Parkinsonism in hospitalized patients for pneumonia may associate to an additional health economic burden of the elderly.
Author Block: T. Jo1, H. Yasunaga2, W. Hasegawa1, Y. Sakamoto1, H. Takeshima1, H. Urushiyama1, Y. Hiraishi1, A. Mitani1, M. Tarui1, G. Tanaka1, T. Nagase1, Y. Yamauchi1; 1Department of Respiratory Medicine, The University of Tokyo Hospital, Tokyo, Japan, 2Department of Clinical Epidemiology and Health Economics, The University of Tokyo, Tokyo, Japan.
Background: Parkinsonism increases with aging and both Parkinsonism and aging has been associated with morbidity and mortality of pneumonia. However, the impact of Parkinsonism on hospitalized elderly patients for pneumonia remain obscure. The aim of this study was to evaluate the impact of Parkinsonism on the course of elderly patients hospitalized for pneumonia. Methods: Using the Japanese Diagnosis Procedure Combination database, we created a matched pair cohort in patients aged 60 years or older hospitalized for pneumonia with or without Parkinsonism. In-hospital mortalities, discharge status, length of stay and total cost during hospitalization were evaluated. We performed a multivariable logistic regression analysis to assess the association between 28-day in-hospital mortality and Parkinsonism. Results: In-hospital mortality for 7, 14 and 28 days were not higher in elderly patients hospitalized for pneumonia with Parkinsonism. However, Patients with Parkinsonism showed significantly longer length of stay, higher total cost during hospitalization and were less likely to discharge home. Multivariate analysis revealed a lower risk for in-hospital mortality in patients with Parkinsonism. Conclusions: We demonstrated that Parkinsonism was not necessarily a risk for in-hospital mortality in pneumonia patients. However, comorbid Parkinsonism in hospitalized patients for pneumonia may associate to an additional health economic burden of the elderly.
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