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A3575 - Key Findings of the Fukuoka Tobacco-Related Lung Disease (FOLD) Registry Study in Japan
Author Block: T. Yanagihara1, S. Ogata-Suetsugu1, N. Hamada1, T. Tsuda2, S. Takata3, N. Inoue4, Y. Kitasato5, K. Yatera6, H. Mukae7, T. Hoshino8, N. Nagata9, K. Watanabe10, C. Yoshii11, Y. Wakata12, S. Tokunaga12, Y. Nakanishi1; 1Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka City, Japan, 2Tsuda Hospital, Kitakyushu, Japan, Kitakyushu City, Japan, 3Research Institute for Diseases of the Chest, National Hospital Organization, Fukuoka Higashi Medical Center, Koga City, Japan, 4Kyushu Rosai hospital, Kitakyushu City, Japan, 5Department of Respiratory Medicine, Kurume General Hospital, Kurume City, Japan, 6University of Occupational Health, Kitakyushu 807 8555, Japan, 7Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki, Japan, 8Kurume Univ, Krume Fukuoka, Japan, 9Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Fukuoka City, Japan, 10Respiratory Medicine, Fukuoka Univ Sch of Medicine, Fukuoka, Japan, 11Department of Respiratory Medicine, Wakamatsu Hospital of the University of Occupational and Environmental Health, Kitakyushu City, Japan, 12Department of Health Services Management and Policy, Graduate School of Medical Science, Kyushu University, Fukuoka City, Japan.
Background: Tobacco smoking causes various smoking-related diseases, death, and economic damage; however, it is reported that approximately 20% of the Japanese population practices smoking. Despite targeted anti-smoking campaigns, tobacco-related deaths are expected to increase in Japan. In the present study, we investigated the current state of tobacco-related lung diseases in Fukuoka Prefecture, Japan. Methods: This is a prospective multi-institutional observational study involving 29 major hospitals covering most of the Fukuoka Prefecture area. This study included patients diagnosed with idiopathic interstitial pneumonia (IIP), chronic obstructive disease (COPD), or combined pulmonary fibrosis and emphysema (CPFE) between September 1, 2013 and April 1, 2016. We collected data regarding background, laboratory and pulmonary function tests, medication history, chest X-ray, chest computed tomography and DNA isolated from peripheral blood. A follow-up surveillance has been planned to include data regarding the exacerbation of disease and death until 5 years of registration. In the present study, we reported the baseline characteristics of the patients registered in this surveillance study. Results: A total of 1024 patients (379 IIP, 491 COPD, and 145 CPFE) from 29 institutions were enrolled in the present study. Among the patients with COPD and CPFE, over 90% were current or former smokers. Conclusion: This study revealed the current status of tobacco-related lung diseases and treatment for these diseases in Fukuoka Prefecture.