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Cannabis Effects in Airflow
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A3580 - Cannabis Effects in Airflow
Author Block: W. Rodriguez1, M. Ortiz-Bonilla1, J. Ramos-Rossy2; 1Pulm/CCM/Sleep, VA Caribbean Healthcare System, San Juan, PR, United States, 2Pneumology and Critical Care, VA Hospital, San Juan, AL, United States.
Introduction
Tobacco smoking is associated with numerous adverse pulmonary outcomes such as: cough, chronic bronchitis, impairment of gas exchange and airway obstruction that leads to chronic obstructive pulmonary disease. The tobacco smoke is composed of multiple ingredients that can cause chronic inflammation to the upper and lower airway (e.g. carbon monoxide, cyanide, acrolein, nitrosamine, reactive oxygen species and some aromatic hydrocarbons). The marijuana (MJ) smoke is composed qualitatively of the same ingredient that are present in the tobacco smoke. The widespread use of cannabis(CN)has raised many concerns over its long-term effect which may be like those side effects caused by tobacco smoking. There are findings suggesting that smoking CN is associated with large airway inflammation, symptoms of chronic bronchitis, increased airway resistance, and lung hyperinflation. Although there is no recent evidence that show that smoking CN can lead to develop symptoms such as COPD. Given the persistently high prevalence of MJ use, abuse, and dependence in the United States, it is important to understand the potential adverse health outcomes that result from both short-term and long-term marijuana smoking. Purpose: investigate lung function changes in patient with previous history of cCN smoking. The hypothesis was that patients with previous history of CN use will have significant changes on pulmonary function test such as air trapping, hyperinflation, increased airway resistance, and decreased functional vital capacity. To test the hypothesis, the study was designed as a cross-sectional study. A pulmonary function test was performed to evaluate patients with history of Cannabis used. Subject were 21-89 year of age, receiving addiction rehabilitation therapy in outpatient and inpatient settings at the VACHS.Results: A total of 22 patients were recruited. The majority of subjects are 56 year old men w an average 20 year hx of CN smoking, 80% using regular cig also, and w obstruction to airflow in 60% of the sample, moderate gradation, resp to bronchodilators. CN smoking is another serious threat to airway irritation/inflammation.
Author Block: W. Rodriguez1, M. Ortiz-Bonilla1, J. Ramos-Rossy2; 1Pulm/CCM/Sleep, VA Caribbean Healthcare System, San Juan, PR, United States, 2Pneumology and Critical Care, VA Hospital, San Juan, AL, United States.
Introduction
Tobacco smoking is associated with numerous adverse pulmonary outcomes such as: cough, chronic bronchitis, impairment of gas exchange and airway obstruction that leads to chronic obstructive pulmonary disease. The tobacco smoke is composed of multiple ingredients that can cause chronic inflammation to the upper and lower airway (e.g. carbon monoxide, cyanide, acrolein, nitrosamine, reactive oxygen species and some aromatic hydrocarbons). The marijuana (MJ) smoke is composed qualitatively of the same ingredient that are present in the tobacco smoke. The widespread use of cannabis(CN)has raised many concerns over its long-term effect which may be like those side effects caused by tobacco smoking. There are findings suggesting that smoking CN is associated with large airway inflammation, symptoms of chronic bronchitis, increased airway resistance, and lung hyperinflation. Although there is no recent evidence that show that smoking CN can lead to develop symptoms such as COPD. Given the persistently high prevalence of MJ use, abuse, and dependence in the United States, it is important to understand the potential adverse health outcomes that result from both short-term and long-term marijuana smoking. Purpose: investigate lung function changes in patient with previous history of cCN smoking. The hypothesis was that patients with previous history of CN use will have significant changes on pulmonary function test such as air trapping, hyperinflation, increased airway resistance, and decreased functional vital capacity. To test the hypothesis, the study was designed as a cross-sectional study. A pulmonary function test was performed to evaluate patients with history of Cannabis used. Subject were 21-89 year of age, receiving addiction rehabilitation therapy in outpatient and inpatient settings at the VACHS.Results: A total of 22 patients were recruited. The majority of subjects are 56 year old men w an average 20 year hx of CN smoking, 80% using regular cig also, and w obstruction to airflow in 60% of the sample, moderate gradation, resp to bronchodilators. CN smoking is another serious threat to airway irritation/inflammation.
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