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Diagnostic and Prognostic Obstruction Degree Based on FEV1 and MEF50 in Elderly Patients that Had Treatment at Zainal Abidin General Hospital Aceh

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A3891 - Diagnostic and Prognostic Obstruction Degree Based on FEV1 and MEF50 in Elderly Patients that Had Treatment at Zainal Abidin General Hospital Aceh
Author Block: S. Bahry1, L. Julisafrida1, H. Priyanto2, S. Saminan3; 1Resident of Pulmonology and Respiratory Medicine, Zainoel Abidin General Hospital / Medical Faculty of Syiah kuala University, Banda Aceh, Indonesia, 2Consultant of Pulmonology and Respiratory Medicine, Zainoel Abidin General Hospital / Medical Faculty of Syiah kuala University, Banda Aceh, Indonesia, 3Head Officer of Departement Physiology, Medical Faculty Of Syiah Kuala University, Banda Aceh, Indonesia.
Abstract Background
The maximal expiratory flow at 50% of the forced vital capacity (MEF50) is the flow where half of forced vital capacity (FVC) remains to be exhaled. Some investigators considers the MEF50 to be more sensitive than the FEV1 for detecting early airway obstruction, but it has a wider ranger of normal values. The aims to determined correlation between age, gender and BMI with the degree of obstruction based on the value of FEV1 and MEF50.
Methods
a cross sectional study, outpatient aged > 45 years, spirometry examination. The data will be analyzed using SPSS with spearman rank nonparametric technique.
Results
Total sample 51 with 41 men and 10 women. Age 45-63 had a mild obstruction 14 (FEV1) and moderate obstruction 8 (MEF50), age 64-80 had a moderate obstruction 9 (FEV1) and severe obstruction 9 (MEF50). Based on sex, men had a moderate obstruction 14 (FEV1) and severe obstruction 14 (MEF50). Based on BMI, 14 mild obstruction (FEV1) and 10 severe obstruction (MEF50). Statistical tests using spearment test found no relationship between the age with the degree of obstruction based on the value of FEV1, p-value 0,185 (>0.05). There is a significant relationship between the degree of obstruction and age based on the value of the MEF50 p-value 0.016 (>0.05). There is no significant relationship between the degree of obstruction and gender based on the value of FEV1 p-value 0,640 (>0.05) and based on the value of the MEF50 p-value 0,789 (>0.05). There is no significant relationship between the degree of obstruction and BMI based on the value of FEV1 p-value 0,415 (>0.05) and based on the value of the MEF50 p-value 0,060 (>0.05).
Conclusion
There is no significant relationships between the age, gender and BMI with the degree of obstruction based on the value of FEV1, and between gender and BMI with the degree of obstruction based on the value of the MEF50. There are significant relationships between the age with the degree of obstruction based on the value of the MEF50.
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