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Use of Narcotics and Benzodiazepines in Hospitalized Patient at High Risk for Obstructive Sleep Apnea: A Retrospective Review of Data from Inpatient Sleep Registry in Urban Tertiary Care Center
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A3969 - Use of Narcotics and Benzodiazepines in Hospitalized Patient at High Risk for Obstructive Sleep Apnea: A Retrospective Review of Data from Inpatient Sleep Registry in Urban Tertiary Care Center
Author Block: A. Niroula, M. Rives-Sanchez, A. Quintos, N. Khandkar, K. Mohiuddin, S. Sharma; Pulmonary and Critical Care, Albert Einstein Medical Center, Philadelphia, PA, United States.
Background:
Obstructive Sleep apnea (OSA) is a common in hospitalized patients. Use of inadvertent narcotics and Benzodiazepines (BZDs) can have a deleterious effect on these patients. Use of these medications in hospitalized patient and its implications in at risk patients has not been well studied. Aim of our study was to determine the prevalence of use of narcotics in high-risk patients for OSA.
Methods:
We did a retrospective review of patient data entered in inpatient sleep registry. Patients admitted in general medicine floors were screened for risk of OSA with STOPBANG questionnaire. Score of more than or equal to 3 were selected as high risk. Retrospective reviews of patient charts were done to select patients on narcotics and/or benzodiazepines regardless of indication. We calculated total percentage of high-risk patients for OSA on narcotics and BZDs. Length of stay of high-risk patient with and without these medications was calculated.
Results:
A Total of 667 patients were determined to be at high risk for OSA with STOPBANG questionnaire. 267 out of 667 (40.02%) of high-risk patients were found to have received narcotics or BZDs while in the hospital. Mean length of stay in patients receiving narcotics and/ or BZDS was 5.5 days versus 5 days in patients not on these medications.
Discussion:
Sedatives and narcotics in OSA patients can worsen apneas and oxygen desaturations. There are limited data on prevalence of use of these medications in hospitalized patient with or at risk of OSA. Our study demonstrates that significant numbers of high-risk patients are inadvertently exposed to sedative/narcotics during their hospital stay. There is also limited data on impact of these drugs in terms of length of stay, adverse effects, escalation of care or other sub-optimal outcomes. We intend to collect further data on these patients to study whether this translates to a worse outcome in these patients.
Conclusion:
Use of inadvertent narcotic and/or sedatives is highly prevalent in hospitalized patient at risk for OSA. Implications of use of these medications may provide insight into ways to reduce sub-optimal outcome in this group.
Author Block: A. Niroula, M. Rives-Sanchez, A. Quintos, N. Khandkar, K. Mohiuddin, S. Sharma; Pulmonary and Critical Care, Albert Einstein Medical Center, Philadelphia, PA, United States.
Background:
Obstructive Sleep apnea (OSA) is a common in hospitalized patients. Use of inadvertent narcotics and Benzodiazepines (BZDs) can have a deleterious effect on these patients. Use of these medications in hospitalized patient and its implications in at risk patients has not been well studied. Aim of our study was to determine the prevalence of use of narcotics in high-risk patients for OSA.
Methods:
We did a retrospective review of patient data entered in inpatient sleep registry. Patients admitted in general medicine floors were screened for risk of OSA with STOPBANG questionnaire. Score of more than or equal to 3 were selected as high risk. Retrospective reviews of patient charts were done to select patients on narcotics and/or benzodiazepines regardless of indication. We calculated total percentage of high-risk patients for OSA on narcotics and BZDs. Length of stay of high-risk patient with and without these medications was calculated.
Results:
A Total of 667 patients were determined to be at high risk for OSA with STOPBANG questionnaire. 267 out of 667 (40.02%) of high-risk patients were found to have received narcotics or BZDs while in the hospital. Mean length of stay in patients receiving narcotics and/ or BZDS was 5.5 days versus 5 days in patients not on these medications.
Discussion:
Sedatives and narcotics in OSA patients can worsen apneas and oxygen desaturations. There are limited data on prevalence of use of these medications in hospitalized patient with or at risk of OSA. Our study demonstrates that significant numbers of high-risk patients are inadvertently exposed to sedative/narcotics during their hospital stay. There is also limited data on impact of these drugs in terms of length of stay, adverse effects, escalation of care or other sub-optimal outcomes. We intend to collect further data on these patients to study whether this translates to a worse outcome in these patients.
Conclusion:
Use of inadvertent narcotic and/or sedatives is highly prevalent in hospitalized patient at risk for OSA. Implications of use of these medications may provide insight into ways to reduce sub-optimal outcome in this group.
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