Event

Obstructive lung diseases including asthma and chronic obstructive pulmonary disease (COPD) involve fibrotic alterations in collagen and elastin fibers, which traditionally have been visualized using histological stains. Over the last 15 years, non-linear optical microscopy (NLOM) has emerged as a powerful research tool (with clinical imaging potential) for visualization of the supramolecular assembly of collagen and elastin fibers in tissues at an unprecedented level of detail, without tissue staining. The learner will gain insight into the recent advances in NLOM imaging modalities, second harmonic generation (SHG) used to image collagen and two-photon excitation fluorescence (TPEF) used to image elastin.