This session will bring together international leaders in Precision Medicine initiatives as well as an inter-disciplinary group of researchers who have made advances in sleep apnea phenotyping and genomic studies of sleep apnea-related traits. The session aims to describe a modern paradigm for resolving heterogeneity of sleep apnea and for identifying risk factors for sleep apnea susceptibility that utilize quantitative phenotyping and genetic analyses. The goals are to challenge clinicians and researchers to consider a broader array of sleep apnea phenotypes both for clinical assessments and in research studies, including use in small and large-scale genetic studies. The session also will make the community aware of recent progress in linking novel sleep apnea phenotypes to genomic risk factors.