This symposium will highlight guidelines and statements on COPD exacerbation, noninvasive ventilation, smoking cessation, lung cancer screening and lymphangioleiomyomatosis (LAM). Speakers will describe the clinical recommendations formulated by the guideline panels, discuss the rationale for each, and critically review the evidence supporting each recommendation. Speakers will also describe how the guidelines provide the foundation for improving care. Speakers include the chairs of the panels that developed the guidelines.