The purpose of this session is to engage researchers, clinicians, educators, trainees and administrators in an effort to address the crisis of burnout syndrome among practicing healthcare workers. This is pertinent to clinicians who care for patients with critical illness, cancer, advanced lung diseases, or children with chronic respiratory illnesses. We will discuss the scope of the problem, including the prevalence, risk factors, and outcomes related to burnout among nurses, advanced practitioners, physicians, and trainees. We will discuss evidence-based solutions and develop a platform to discuss future directions for research, policy, and clinical practice to overcome the burden of burnout.