Over the past several decades survival has increased dramatically amongst children with many chronic respiratory conditions including cystic fibrosis, chronic respiratory insufficiency, and neuromuscular disease. As a result, health systems need to develop and support programs to improve the transition from pediatric to adult focused health care. Adolescents and young adults are often ill equipped to complete this transition successfully, formalized transition programs are uncommon, and resources for certain populations are lacking within adult-focused health care systems. This symposium will address the challenges patients, their caregivers and clinicians have in transitioning care, and will review evidence-based tools used to foster this transition.