This course provides state of the art information on the evaluation and management of severe asthma in children. Speakers will review best practices for evaluation including medication adherence monitoring and support. Discussions will range from the clinically relevant biologic mechanisms of asthma to addressing whether phenotyping and endotyping can improve outcomes. We will also discuss strategies for developing partnerships with other health care disciplines and community resources in order to achieve a patient-centered approach. The course includes small group review of difficult cases and discussion of unmet needs. Speakers will also demonstrate appropriate use of targeted therapies, and describe best practices for monitoring for adverse effects of therapies.