You are cordially invited to an AstraZeneca sponsored non-CME dinner program on emerging mechanisms of disease in asthma and COPD. This faculty led symposium will examine asthma and COPD from the phenotype/endotype perspective to demonstrate the importance of relating observable characteristics to mechanisms of disease. This presentation will include a discussion of our current understanding of eosinophils and other immunologic pathways and their association with disease severity, lung function decline and negative outcomes. The program will conclude with a prospective look at the evolving goals of therapy and the questions that must be addressed to target mechanisms of disease toward the goal of delivering patient centric care.